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49 次 LongGene熒光定量PCR助力中科大團(tuán)隊(duì)榮登Nature子刊 2025-7-18
綜合性Top期刊中科大發(fā)表成果近日，中國科學(xué)技術(shù)大學(xué)鮑堅(jiān)強(qiáng)課題組，聯(lián)合山東大學(xué)劉洪彬課題組，在Cell Death & Differentiation發(fā)表題為Combinatorial tagging generates a multi-purpose k
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180 次 KLF4 和 AMPK 在內(nèi)皮細(xì)胞中脈動(dòng)切應(yīng)力抑制糖酵解過程中的作用 2025-7-16
Roles of KLF4 and AMPK in the inhibition of glycolysis by pulsatile shear stress in endothelial cellsKeywords: AMPK; KLF4; epigenetics; GCKR; glycolysis.內(nèi)皮細(xì)胞覆蓋動(dòng)脈管腔并直接接
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218 次 拉伸通過增強(qiáng)成纖維細(xì)胞中內(nèi)皮素受體B和TRPC3 的表達(dá)來促進(jìn)傷口收縮 2025-7-15
Stretching Promotes Wound Contraction Through Enhanced Expression of Endothelin Receptor B and TRPC3 in FibroblastsKeywords: Stretching; Wound contraction; Endothelin Receptor B; T
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245 次 壓力響應(yīng)型 miRNA - 5703 的過表達(dá)抑制壓力誘導(dǎo)的肝癌生長和轉(zhuǎn)移 2025-7-9
Overexpression of pressure-responsive miRNA-5703 inhibits pressure-induced growth and metastasis of liver cancerKeywords: liver cancer; metastasis; miRNA-5703; portal hypertension;
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229 次 成纖維細(xì)胞中張力敏感的 HOX 基因表達(dá)用于差異瘢痕形成 2025-7-8
Tension-sensitive HOX gene expression in fibroblasts for differential scar formationKeywords: Scar formation, Hypertrophic scar; Keloid; Wound healing; Tension; Tension change; Ten
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302 次 C/EBPβ 拮抗劑誘導(dǎo)巨噬細(xì)胞促炎極化增強(qiáng)抗腫瘤免疫 2025-7-3
The C/EBPβ antagonist peptide lucicebtide (ST101) induces macrophage polarization toward a pro-inflammatory phenotype and enhances anti-tumor immune responsesKeywords: C/EBP&b
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345 次 小鼠主動(dòng)脈應(yīng)力激活平滑肌細(xì)胞適應(yīng)性程序維持強(qiáng)度防動(dòng)脈瘤和夾層 2025-6-30
Aortic Stress Activates an Adaptive Program in Thoracic Aortic Smooth Muscle Cells That Maintains Aortic Strength and Protects Against Aneurysm and Dissection in MiceKeywords: aort
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411 次 成骨細(xì)胞線粒體氧化應(yīng)激或自噬減少不足以模擬衰老對骨機(jī)械反應(yīng)性損害 2025-6-24
Mitochondrial oxidative stress or decreased autophagy in osteoblast lineage cells is not sufficient to mimic the deleterious effects of aging on bone mechanoresponsivenessKeywords:
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249 次 苔蘚抑素-1（Bryostatin-1）通過抑制內(nèi)皮細(xì)胞自噬改善動(dòng)脈功能 2025-6-24
Bryostatin-1 improves function in arteries with suppressed endothelial cell autophagyKeywords: Aging; Bryostatin-1; Endothelial cell; Nitric oxide.內(nèi)皮功能障礙是心血管衰老的標(biāo)志，內(nèi)
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292 次 Piezo1 對抗與衰老相關(guān)的皮質(zhì)骨丟失 2025-6-24
Piezo1 opposes age-associated cortical bone lossKeywords: Piezo1; age-associated bone loss; endocortical bone resorption; mechanical stimulation.衰老會(huì)導(dǎo)致松質(zhì)骨和皮質(zhì)間隔的骨質(zhì)流失
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284 次 機(jī)械激活的間充質(zhì)衍生骨細(xì)胞通過細(xì)胞外囊泡介導(dǎo)的機(jī)制驅(qū)動(dòng)血管生成 2025-6-23
Mechanically activated mesenchymal-derived bone cells drive vessel formation via an extracellular vesicle mediated mechanismKeywords: Osteoblast; VEGF; angiogenesis; mechanobiology
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210 次 血管炎性疾病和內(nèi)皮表型 2025-6-17
Vascular Inflammatory Diseases and Endothelial PhenotypesKeywords: EC phenotypes; endothelial cell; inflammation; vascular diseases.內(nèi)皮細(xì)胞排列在管腔表面，充當(dāng)分隔血液和周圍組織的
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172 次 微管蛋白乙酰化增強(qiáng)機(jī)械應(yīng)力下小梁網(wǎng)細(xì)胞的微管穩(wěn)定性 2025-6-16
Tubulin Acetylation Enhances Microtubule Stability in Trabecular Meshwork Cells Under Mechanical StressKeywords: trabecular meshwork, glaucoma, tubulin acetylation, mechanical stre
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354 次 拉伸誘導(dǎo)的內(nèi)皮細(xì)胞單層損傷的相關(guān)研究 2025-6-10
Stretch-induced damage in endothelial monolayersKeywords: Aging; Cell mechanics; Endothelium; Mechanobiology; Senescence; Stretch.由于血流的脈動(dòng)性，包括流體剪切力、壓力和循環(huán)拉伸在
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388 次 視網(wǎng)膜神經(jīng)節(jié)細(xì)胞經(jīng)IL-12-SCGF-β串?dāng)_誘導(dǎo)干細(xì)胞衍生的神經(jīng)保護(hù)作用 2025-6-9
Retinal ganglion cells induce stem cell-derived neuroprotection via IL-12 to SCGF-β crosstalkKWS：Retinal ganglion cells；stem cell；neuroprotection；IL-12；SCGF-β；cross
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453 次 血管內(nèi)皮-間充質(zhì)串?dāng)_通過 Notch 信號(hào)驅(qū)動(dòng)人成骨細(xì)胞的成骨分化 2025-6-4
Endothelial-mesenchymal crosstalk drives osteogenic differentiation of human osteoblasts through Notch signalingKeywords: Co-culture; Endothelial cells; Notch signaling; Osteoblast
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374 次 TRPV4 抑制劑和機(jī)械負(fù)荷對減輕炎癥的協(xié)同作用 2025-6-3
Synergetic role of TRPV4 inhibitor and mechanical loading on reducing inflammationKeywords: anti-inflammatory phenotype; inhibition, mechanical loading; macrophage polarization; mi
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471 次 小鼠大學(xué)問之Cre-lox系統(tǒng)的常見問題與解答匯總 2025-5-29
上一期我們給大家介紹了Cre-lox系統(tǒng)的基本原理，不知道大家有沒有理解呢？點(diǎn)擊查看：小鼠大學(xué)問 | Cre-Lox系統(tǒng)核心原理全解析本期我們給大家?guī)砹薈re-lox系統(tǒng)的一些常見問題。幫助大家更好的利
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419 次 I 類 PI3Ks 激活小梁網(wǎng)細(xì)胞中拉伸誘導(dǎo)的自噬 2025-5-27
Class I PI3Ks activate stretch-induced autophagy in trabecular meshwork cellsKeywords: Autophagy; Glaucoma; Mechanical stress; PI3K; Primary cilia; Trabecular meshwork.眼壓升高（IO
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340 次 內(nèi)皮 IGFBP6 抑制血管炎癥和動(dòng)脈粥樣硬化 2025-5-26
Endothelial IGFBP6 suppresses vascular inflammation and atherosclerosisKWS：IGFBP6；vascular inflammation；atherosclerosis動(dòng)脈粥樣硬化通常發(fā)生在血流紊亂（DF）區(qū)域，例如動(dòng)脈分支或彎
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