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765 次 循環(huán)牽張應(yīng)力通過(guò)整合素αVβ3-肌動(dòng)蛋白絲軸調(diào)控MSCs早期成骨分化 2024-12-23
Regulation of the integrin αVβ3- actin filaments axis in early osteogenic differentiation of human mesenchymal stem cells under cyclic tensile stressKeywords: Integrin &
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1286 次 FAK 通過(guò) Drp1 調(diào)控心肌細(xì)胞線粒體裂變和功能 2024-12-16
FAK regulates cardiomyocyte mitochondrial fission and function through Drp1Keywords: Drp1; FAK; fibronectin; mitochondrial fission.線粒體對(duì)于心肌細(xì)胞的能量產(chǎn)生至關(guān)重要，其功能障礙與
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1635 次 機(jī)械應(yīng)力經(jīng)TGF-β1 激活 Smad2/3 并抑制 NF-κB 以防軟骨細(xì)胞焦亡 2024-12-16
Mechanical stress protects against chondrocyte pyroptosis through TGF-β1-mediated activation of Smad2/3 and inhibition of the NF-κB signaling pathway in an osteoarthriti
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877 次 動(dòng)脈粥樣硬化中血流紊亂會(huì)損害MerTK介導(dǎo)的主動(dòng)脈內(nèi)皮細(xì)胞的胞葬作用 2024-12-9
Disturbed flow impairs MerTK-mediated efferocytosis in aortic endothelial cells during atherosclerosisKeywords: Disturbed flow; MerTK; RNA-seq; atherosclerosis; efferocytosis; prot
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832 次 機(jī)械敏感的多囊蛋白1促進(jìn)骨膜干/祖細(xì)胞在骨折愈合中的骨軟骨分化 2024-12-9
Mechanosensitive protein polycystin-1 promotes periosteal stem/progenitor cells osteochondral differentiation in fracture healingKeywords: Fracture healing; Mechanical stress; Peri
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731 次 TNFSF12/TWEAK調(diào)節(jié)結(jié)腸炎性成纖維細(xì)胞并促其與單核細(xì)胞相互作用 2024-12-2
The TNFSF12/TWEAK Modulates Colonic Inflammatory Fibroblast Differentiation and Promotes Fibroblast-Monocyte InteractionsKWS：TNFSF12/TWEAK；Colonic Inflammatory Fibroblast；Differ
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671 次 miR-342-5p通過(guò)抑制 MYC增強(qiáng)內(nèi)皮細(xì)胞對(duì)剪切力的動(dòng)脈化響應(yīng) 2024-12-2
miR-342-5p downstream to Notch enhances arterialization of endothelial cells in response to shear stress by repressing MYCKeywords: MT: Non-coding RNAs; Notch; arterialization; end
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917 次 激活的SIRT1 通過(guò)增強(qiáng) H 型血管生成和骨形成的耦聯(lián)來(lái)促進(jìn)骨修復(fù) 2024-11-25
SIRT1 activation promotes bone repair by enhancing the coupling of type H vessel formation and osteogenesisKWS：SIRT1；bone repair；type H vessel formation；osteogenesis骨缺損可由感
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1362 次 血管內(nèi)皮細(xì)胞機(jī)械敏感基因在動(dòng)脈粥樣硬化形成和治療中的研究進(jìn)展 2024-11-25
Recent advances of mechanosensitive genes in vascular endothelial cells for the formation and treatment of atherosclerosisKeywords: Atherosclerosis; Blood flow; Endothelial cell; M
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790 次 CD97 在壓縮下通過(guò) Rap1a/ERK 通路抑制破骨細(xì)胞分化 2024-11-18
CD97 inhibits osteoclast differentiation via Rap1a/ERK pathway under compressionSubject terms: Orthodontics, Cell signalling正畸治療是通過(guò)正畸牙齒移動(dòng)（OTM）矯正咬合不正。OTM 是一種
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2009 次 Piezo1 介導(dǎo)的機(jī)械轉(zhuǎn)導(dǎo)導(dǎo)致血流紊亂誘導(dǎo)的動(dòng)脈粥樣硬化內(nèi)皮炎癥 2024-11-18
Piezo1‐Mediated Mechanotransduction Contributes to Disturbed Flow‐Induced Atherosclerotic Endothelial InflammationKeywords: Piezo1; atherosclerosis; endothelial cells; inflammati
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817 次 綠茶化合物EGCG在子癇前期的體外靜態(tài)和剪切應(yīng)力模型中的抗氧化作用 2024-11-16
EGCG, a Green Tea Compound, Increases NO Production and Has Antioxidant Action in a Static and Shear Stress In Vitro Model of PreeclampsiaKeywords: EGCG; NO; antioxidant; endotheli
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818 次 電壓門(mén)控性鈣通道α2δ亞基-1調(diào)控結(jié)腸癌進(jìn)展并影響其微環(huán)境 2024-10-28
CACNA2D1 regulates the progression and influences the microenvironment of colon cancerKeywords: CACNA2D1; Colon cancer; Fibroblast; Voltage-gated calcium channel; p53.近年來(lái)，由于化
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680 次 人牙周膜間充質(zhì)基質(zhì)細(xì)胞通過(guò)旁分泌和細(xì)胞接觸介導(dǎo)對(duì)CD4+T的免疫調(diào)節(jié) 2024-10-28
Paracrine- and cell-contact-mediated immunomodulatory effects of human periodontal ligament-derived mesenchymal stromal cells on CD4+ T lymphocytesKeywords: CD4+ T lymphocytes; Co-
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800 次 衰老誘導(dǎo)內(nèi)皮受損金屬蛋白酶17脫落連接粘附分子-A導(dǎo)致動(dòng)脈重塑 2024-10-28
Aging-induced impaired endothelial wall shear stress mechanosensing causes arterial remodeling via JAM-A/F11R shedding by ADAM17Keywords: Aging; Endothelium dysfunction; F11R; Junc
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999 次 BACH1 基因的缺失通過(guò)減少內(nèi)皮炎癥減輕動(dòng)脈粥樣硬化 2024-10-28
Deletion of BACH1 Attenuates Atherosclerosis by Reducing Endothelial InflammationKeywords: BACH1; YAP; atherosclerosis; endothelial inflammation; hemodynamics.動(dòng)脈粥樣硬化是冠狀動(dòng)脈
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1915 次 Cre-LoxP 系統(tǒng)助力條件性基因敲除動(dòng)物模型研究 2024-10-25
在生物醫(yī)學(xué)研究和基因功能探索中，條件性基因敲除技術(shù)占據(jù)了舉足輕重的地位。其中，Cre-LoxP 系統(tǒng)以其獨(dú)特的工作原理和廣泛的應(yīng)用場(chǎng)景，成為了研究基因功能不可或缺的利器。今天，我們就來(lái)深入了
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737 次 流體剪切應(yīng)力通過(guò)NKG2D增強(qiáng)自然殺傷細(xì)胞對(duì)循環(huán)腫瘤細(xì)胞的細(xì)胞毒性 2024-10-25
Fluid shear stress enhances natural killer cell's cytotoxicity toward circulating tumor cells through NKG2D-mediated mechanosensingTopics：Mechanical stress, Cytotoxicity, Degr
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909 次 與體外循環(huán)相關(guān)剪切應(yīng)力誘導(dǎo)單核細(xì)胞炎性細(xì)胞因子和壞死性凋亡的表達(dá) 2024-10-25
Shear stress associated with cardiopulmonary bypass induces expression of inflammatory cytokines and necroptosis in monocytesKeywords: Calcium signaling; Cardiology; Cytokines; Inf
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876 次 線粒體蛋白去琥珀酰化通過(guò)調(diào)節(jié)線粒體穩(wěn)態(tài)介導(dǎo)壓縮誘導(dǎo)的椎間盤(pán)退變 2024-10-25
SIRT5-related desuccinylation modification of AIFM1 protects against compression-induced intervertebral disc degeneration by regulating mitochondrial homeostasisSubject terms: Dise
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