20 次LongGene熒光定量PCR助力中科大團隊榮登Nature子刊 2025-7-18
綜合性Top期刊中科大發表成果近日,中國科學技術大學鮑堅強課題組,聯合山東大學劉洪彬課題組,在Cell Death & Differentiation發表題為Combinatorial tagging generates a multi-purpose k
160 次KLF4 和 AMPK 在內皮細胞中脈動切應力抑制糖酵解過程中的作用 2025-7-16
Roles of KLF4 and AMPK in the inhibition of glycolysis by pulsatile shear stress in endothelial cellsKeywords: AMPK; KLF4; epigenetics; GCKR; glycolysis.內皮細胞覆蓋動脈管腔并直接接
231 次DNA甲基化技術助力揭示IRF1在創傷性顱腦損傷中的表觀調控機制 2025-7-15
近日,空軍軍醫大學唐都醫院神經外科崔文興博士為第一作者,白浩博士和郭成鉉碩士為共同第一作者;屈延教授為論文通訊作者,葛順楠教授、劉海嘯副研究員為共同通訊作者在Science子刊《Science T
214 次拉伸通過增強成纖維細胞中內皮素受體B和TRPC3 的表達來促進傷口收縮 2025-7-15
Stretching Promotes Wound Contraction Through Enhanced Expression of Endothelin Receptor B and TRPC3 in FibroblastsKeywords: Stretching; Wound contraction; Endothelin Receptor B; T
420 次血漿ChIP-seq的cfDNA組蛋白修飾分析揭示晚期前列腺癌表型異質性 2025-7-10
近日,美國國家癌癥研究所David Y. Takeda和加拿大哥倫比亞大學Alexander W. Wyatt、Cameron Herberts團隊合作,利用血漿游離細胞DNA(cell–free DNA,cfDNA)的染色質免疫沉淀測序(cfCh
243 次壓力響應型 miRNA - 5703 的過表達抑制壓力誘導的肝癌生長和轉移 2025-7-9
Overexpression of pressure-responsive miRNA-5703 inhibits pressure-induced growth and metastasis of liver cancerKeywords: liver cancer; metastasis; miRNA-5703; portal hypertension;
301 次C/EBPβ 拮抗劑誘導巨噬細胞促炎極化增強抗腫瘤免疫 2025-7-3
The C/EBPβ antagonist peptide lucicebtide (ST101) induces macrophage polarization toward a pro-inflammatory phenotype and enhances anti-tumor immune responsesKeywords: C/EBP&b
343 次小鼠主動脈應力激活平滑肌細胞適應性程序維持強度防動脈瘤和夾層 2025-6-30
Aortic Stress Activates an Adaptive Program in Thoracic Aortic Smooth Muscle Cells That Maintains Aortic Strength and Protects Against Aneurysm and Dissection in MiceKeywords: aort
409 次成骨細胞線粒體氧化應激或自噬減少不足以模擬衰老對骨機械反應性損害 2025-6-24
Mitochondrial oxidative stress or decreased autophagy in osteoblast lineage cells is not sufficient to mimic the deleterious effects of aging on bone mechanoresponsivenessKeywords:
248 次苔蘚抑素-1(Bryostatin-1)通過抑制內皮細胞自噬改善動脈功能 2025-6-24
Bryostatin-1 improves function in arteries with suppressed endothelial cell autophagyKeywords: Aging; Bryostatin-1; Endothelial cell; Nitric oxide.內皮功能障礙是心血管衰老的標志,內